4,4'-Dimethoxytrityl chloridewani m nucleoside da nucleotide kungiyar kare da kuma kawar da wakili.
Ma'ana:DMT-Cl
Lambar CAS:40615-36-9
Kayayyaki
Tsarin sinadarai
Nauyin Kwayoyin Halitta
Ajiya Zazzabi
Matsayin narkewa
Tsafta
Na waje
Saukewa: C21H19ClO2
338.82 g/mol
2 ~ 8 ℃
120-125 ℃
≥98%
Pink Crystalline
Kamar yadda mahimman abubuwan sarƙoƙi na acid nucleic, nucleosides da nucleotides suna taka muhimmiyar rawa wajen watsa bayanan kwayoyin halitta.Duk da haka, saboda halayen halayensu da sauƙi na lalacewa, nucleosides da nucleotides suna buƙatar ƙwararrun reagents don kare su yayin haɗuwa.DMTCl4'Dimethoxytrityl (DMTCl) ƙungiya ce mai matukar tasiri mai karewa da kawar da wakili wanda ya canza kariyar nucleosides da nucleotides yayin haɗuwa.
DMTCl wakili ne na kariyar hydroxyl wanda ke zaɓin amsawa tare da ƙungiyoyin hydroxyl na nucleosides da nucleotides yayin haɗin gwiwa don samar da ƙungiyar kariya ta wucin gadi wanda ke hana nucleosides da nucleotides amsawa tare da sauran sinadarai.Wannan rukunin kariya na wucin gadi ana samun sauƙin cirewa bayan haɗuwa, yana barin tsarkakakken nucleosides ko nucleotides.
Saboda kyakkyawan reactivity da selectivity,DMTClAna amfani da shi azaman rukuni mai kariya da kawar da wakili a cikin haɗin DNA, RNA da sauran acid nucleic.Yana da amfani musamman don haɗin oligonucleotide inda ake buƙatar daidaitaccen iko akan matsayin nucleotide da jerin.
Bugu da ƙari, yin aiki a matsayin mai karewa da kuma kawar da kungiya, DMTCl shine mai kare hydroxyl mai karfi na nucleosides da nucleotides.Yana kare ƙungiyoyin hydroxyl na nucleosides da nucleotides daga iskar shaka, raguwa, da sauran halayen da zasu iya lalata su yayin haɗuwa.
A takaice,DMTCl4 4' dimetoxytritylkayan aiki ne mai mahimmanci don haɗin nucleosides da nucleotides.Kyakkyawan reactivity, zaɓaɓɓen zaɓi da haɓakawa sun sa ya zama ƙungiyar manufa mai karewa da kawar da wakili da wakili na kare hydroxyl don DNA, RNA da sauran haɗin acid nucleic.Idan kuna buƙatar babban inganci kuma ingantaccen kariya na nucleosides da nucleotides yayin haɗuwa, kada ku kalli DMTCl.
Lokacin aikawa: Juni-08-2023